Epidermal and follicular calciphylaxis

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Epidermal and follicular calciphylaxis.

A patient with secondary hyperparathyroidism due to chronic renal failure developed epidermal and follicular calcification without concomitant dermal calcification in the lesions of toxic epidermal necrolysis. We propose that the combination of keratinocyte necrosis and an elevated serum calcium-phosphorus product resulted in epidermal calciphylaxis.

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Calciphylaxis

however there are adequate discussions of epidemiology, phage anatomy, and the relation of viruses to cancer, as well as other topics which will intrigue the more medically oriented reader. A particularly valuable aspect of the book is that facts are discussed in relation to the research by means of which they were originally discovered or tested. The research is treated both by topic and chron...

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Calciphylaxis

Fig. 1. Dry gangrene of the fingers (A and B) and dusky red discoloration of the right great toe (C) are shown. Progression of the gangrene of the fingers (D and E) and development of gangrenous necrosis of the toes (F) are shown. Plain radiographs demonstrating marked vascular calcification of the hands and feet (G–J). Skin biopsy revealing calcification (K) and microthrombosis (L and M) of sm...

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Calciphylaxis

Figure 1. Right leg with painful ulcer demonstrating thrombosed blood vessels, saponified fat, and ischemic skin necrosis. DESCRIPTION A 56-year-old man presented with a wound of the right leg for 6 weeks that progressed from a linear ulceration with surrounding erythema to an excruciatingly painful ulcer with fat saponification and visible thrombosed vessels. His medical history was significan...

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Flow Cytometry of Human Primary Epidermal and Follicular Keratinocytes

OBJECTIVE The aim of this study was to characterize using flow cytometry cultured human primary keratinocytes isolated from the epidermis and hair follicles by different methods. METHODS Human keratinocytes derived from discarded fragments of total skin and scalp hair follicles from patients who underwent plastic surgery in the Plastic Surgery Division at UNIFESP were used. The epidermal kera...

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ژورنال

عنوان ژورنال: Journal of Cutaneous Pathology

سال: 1988

ISSN: 0303-6987,1600-0560

DOI: 10.1111/j.1600-0560.1988.tb00560.x